Katherine holds a D.Phil. in Organic Chemistry from the University of Oxford for her work on inhibitors of epigenetic proteins. She has worked in drug discovery across a variety of disease areas and drug classes in industry and academia and has been a member of the medicinal chemistry team at the Alzheimer’s Research UK Oxford Drug Discovery Institute (ODDI) since 2015.
Katherine is a team leader in the medicinal chemistry group contributing to a range of projects in the ODDI portfolio.
Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides.
O'Brien DP. et al, (2023), Mol Cell Proteomics, 22
Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides
O’Brien DP. et al, (2022)
USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.
Rusilowicz-Jones EV. et al, (2020), Life Sci Alliance, 3