Chemical probes for Alzheimer’s disease targets
Journal article
Aiken SG. et al, (2026), Essays in Biochemistry
α-Synuclein blocks endoplasmic reticulum co-translational protein translocation early in Parkinson's disease.
Journal article
Lam CL. et al, (2026), Nat Commun, 17
SoftHybrid: A Hybrid Imputation Algorithm Optimized for Single-Cell Proteomics Data.
Journal article
Shi Y. et al, (2026), J Proteome Res
Cross-Ancestry Proteogenomic Analyses Identified New Therapeutic Insights for Ischemic Heart Disease.
Journal article
Mazidi M. et al, (2026), J Am Coll Cardiol
The changing face of UK academic drug screening in the past decade.
Journal article
Baronio R. and Ebner D., (2026), Nat Rev Drug Discov
AI-assisted fragment-based drug discovery of SARS-CoV-2 macrodomain binders validated by NMR and X-ray crystallography.
Journal article
Aledavood E. et al, (2026), Commun Chem
Multiomic profiling of responses to clinical and novel bisphosphonates reveals extraskeletal effects on ageing related signatures.
Journal article
Lu J. et al, (2026), Signal Transduct Target Ther, 11
Structures of the human sodium-citrate cotransporter NaCT with and without substrates.
Preprint
Sauer DB. et al, (2026)
TNFR2 Agonism as a Sex-Specific Therapy for Novel Osteoarthritis-Induced Cardiac Dysfunction.
Journal article
Prasoon P. et al, (2026), bioRxiv
The KDM6 histone H3K27me3 demethylase inhibitor GSK-J4 induces metal and stress responses in multiple myeloma cells.
Journal article
Cribbs AP. et al, (2026), RSC Chem Biol
Molecular Solution to the Paradox of Ancient Brain Preservation.
Journal article
Morton-Hayward A. et al, (2026), J Proteome Res
CDIN1-Codanin-1 complex defective in congenital dyserythropoietic anaemia type I is an RNA nuclease.
Conference paper
Brolih S. et al, (2026), Nat Commun
Functional role of a structural water in the elevator domain of dicarboxylate transporter VcINDY.
Journal article
Daab A. et al, (2026), PNAS Nexus, 5
Towards light-coupled sample preparation for time-resolved cryoEM studies.
Journal article
Hadjidemetriou K. et al, (2026), IUCrJ, 13, 395 - 408
