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Publications

Kalirin as a Novel Treatment Target for Cognitive Dysfunction in Schizophrenia.

Mould AW. et al, (2022), CNS Drugs, 36, 1 - 16

Cytoskeletal protein degradation in brain death donor kidneys associates with adverse post-transplant outcomes.

Vaughan RH. et al, (2021), Am J Transplant

Cytoskeletal protein degradation in brain death donor kidneys associates with adverse post-transplant outcomes.

Vaughan RH. et al, (2021), Am J Transplant

FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency.

Rota IA. et al, (2021), Sci Adv, 7

Target 2035-update on the quest for a probe for every protein

Mueller S. et al, (2021), RSC MEDICINAL CHEMISTRY

Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons

Tanudjojo B. et al, (2021), Nature Communications, 12

Interplay Between KRAS and LZTR1 Protein Turnover, Controlled by CUL3/LZTR1 E3 Ubiquitin Ligase, is Disrupted by KRAS Mutations

Damianou A. et al, (2021)

Variable skeletal phenotypes associated with biallelic variants in PRKG2.

Pagnamenta AT. et al, (2021), J Med Genet

Advancing Mechanistic Understanding and Biomarker Development in Amyotrophic Lateral Sclerosis.

Thompson AG. et al, (2021), Expert Rev Proteomics

Anti-spike antibody response to natural SARS-CoV-2 infection in the general population.

Wei J. et al, (2021), Nat Commun, 12

Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection.

Munnur D. et al, (2021), Nat Immunol

Expanding the phenotypic spectrum of BCS1L-related mitochondrial disease

Hikmat O. et al, (2021), ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY

Turning high-throughput structural biology into predictive inhibitor design

Saar K. et al, (2021)

USP28 deletion and small molecule inhibition destabilises c-MYC and elicits regression of squamous cell lung carcinoma.

Ruiz EJ. et al, (2021), Elife, 10

Author Correction: A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation.

Nizami S. et al, (2021), Sci Rep, 11

Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains.

Elliott PR. et al, (2021), Cell Rep, 37

Biallelic variants in SLC38A3 encoding a glutamine transporter cause epileptic encephalopathy.

Marafi D. et al, (2021), Brain

Immunodominance complexity: lessons yet to be learned from dominant T cell responses to SARS-COV-2

Wellington D. et al, (2021), Current Opinion in Virology, 50, 183 - 191

Age-dependent changes in protein incorporation into collagen-rich tissues of mice by in vivo pulsed SILAC labelling

Ariosa-Morejon Y. et al, (2021), eLife, 10

Development of a Selective Dual Discoidin Domain Receptor (DDR)/p38 Kinase Chemical Probe.

Röhm S. et al, (2021), J Med Chem, 64, 13451 - 13474

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