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Publications

Proteomic analysis of machine perfusion solution from brain dead donor kidneys reveals that elevated complement, cytoskeleton and lipid metabolism proteins are associated with 1-year outcome.

van Leeuwen LL. et al, (2021), Transpl Int, 34, 1618 - 1629

Discovery of a Potent Dual SLK/STK10 Inhibitor Based on a Maleimide Scaffold.

Serafim RAM. et al, (2021), J Med Chem

Identification, mapping and relative quantitation of SARS-CoV-2 Spike glycopeptides by Mass-Retention Time Fingerprinting.

Chalk R. et al, (2021), Commun Biol, 4

A Modified Density Gradient Proteomic-Based Method to Analyse Endolysosomal Proteins in Cardiac Tissue

Ayagama T. et al, (2021), iScience, 102949 - 102949

Diabetic mitochondria are resistant to palmitoyl CoA inhibition of respiration, which is detrimental during ischemia.

Kerr M. et al, (2021), FASEB J, 35

A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation.

Nizami S. et al, (2021), Sci Rep, 11

Proteomic Signature of Dysfunctional Circulating Endothelial Colony‐Forming Cells of Young Adults

Tan CMJ. et al, (2021), Journal of the American Heart Association

Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain.

Brand M. et al, (2021), J Med Chem

An observational cohort study on the incidence of SARS-CoV-2 infection and B.1.1.7 variant infection in healthcare workers by antibody and vaccination status.

Lumley SF. et al, (2021), Clin Infect Dis

Conformational plasticity of the ULK3 kinase domain.

Mathea S. et al, (2021), Biochem J

Recurrent de novo missense variants in GNB2 can cause syndromic intellectual disability.

Tan NB. et al, (2021), J Med Genet

Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.

Szykowska A. et al, (2021), Structure

Deceased donor kidney degradomics suggest cytoskeletal proteolytic processes impact post-transplant graft function

Vaughan RH. et al, (2021)

There is no market for new antibiotics: this allows an open approach to research and development

Klug DM. et al, (2021), Wellcome Open Research, 6, 146 - 146

Quantitative SARS-CoV-2 anti-spike responses to Pfizer-BioNTech and Oxford-AstraZeneca vaccines by previous infection status.

Eyre DW. et al, (2021), Clin Microbiol Infect

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function.

Oftedal BE. et al, (2021), Commun Biol, 4

The structural basis of fatty acid elongation by the ELOVL elongases.

Nie L. et al, (2021), Nat Struct Mol Biol, 28, 512 - 520

Sensing Enzyme Activation Heat Capacity at the Single-Molecule Level Using Gold-Nanorod-Based Optical Whispering Gallery Modes

Subramanian S. et al, (2021), ACS Applied Nano Materials, 4, 4576 - 4583

Exploring protein hotspots by optimized fragment pharmacophores.

Bajusz D. et al, (2021), Nat Commun, 12

Kawasaki Disease Patient Stratification and Pathway Analysis Based on Host Transcriptomic and Proteomic Profiles.

Jackson H. et al, (2021), Int J Mol Sci, 22

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