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Publications

T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles.

Céspedes PF. et al, (2022), Nat Commun, 13

Author Correction: Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.

Zheng Y. et al, (2022), Nat Commun, 13

Protocol paper: a multi-center, double-blinded, randomized, 6-month, placebo-controlled study followed by 12-month open label extension to evaluate the safety and efficacy of Saracatinib in Fibrodysplasia Ossificans Progressiva (STOPFOP).

Smilde BJ. et al, (2022), BMC Musculoskelet Disord, 23

Factor inhibiting HIF can catalyse two asparaginyl-hydroxylations in VNVN motifs of ankyrin fold proteins.

Leissing TM. et al, (2022), J Biol Chem

Chronic inflammatory arthritis drives systemic changes in circadian energy metabolism.

Downton P. et al, (2022), Proc Natl Acad Sci U S A, 119

Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity.

Govender P. et al, (2022), J Med Chem

Snapshots of actin and tubulin folding inside the TRiC chaperonin.

Kelly JJ. et al, (2022), Nat Struct Mol Biol

SAMPL7 protein-ligand challenge: A community-wide evaluation of computational methods against fragment screening and pose-prediction.

Grosjean H. et al, (2022), J Comput Aided Mol Des

Galaxy workflows for fragment-based virtual screening: a case study on the SARS-CoV-2 main protease.

Bray S. et al, (2022), J Cheminform, 14

Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation

Chen Z. et al, (2022), Cell Death & Differentiation

USP18 is an essential regulator of muscle cell differentiation and maturation

Olie CS. et al, (2022)

The first human importin-beta-related disorder: syndromic thoracic aortic aneurysm caused by bi-allelic loss-of-function variants in IPO8

Van Gucht I. et al, (2022), EUROPEAN JOURNAL OF HUMAN GENETICS, 30, 5 - 6

Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus.

Brawley DN. et al, (2022), Nat Chem Biol

Targeted delivery of galunisertib attenuates fibrogenesis in an integrated ex vivo renal transplant and fibrosis model

van Leeuwen L. et al, (2022)

Deep topographic proteomics of a human brain tumour

Davis S. et al, (2022)

Fragment libraries designed to be functionally diverse recover protein binding information more efficiently than standard structurally diverse libraries

Carbery A. et al, (2022)

ABPP-HT*-Deep Meets Fast for Activity-Based Profiling of Deubiquitylating Enzymes Using Advanced DIA Mass Spectrometry Methods.

Jones HBL. et al, (2022), Int J Mol Sci, 23

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

Ahern DJ. et al, (2022), Cell, 185, 916 - 938.e58

A Single-Cell Atlas of the Leiomyoma Vascular Capsule Reveals Activation of Endothelial and Immune Cells

Philpott M. et al, (2022), REPRODUCTIVE SCIENCES, 29, 205 - 205

Towards an Understanding of the Pathomechanisms of Uterine Fibroids and Associated Heavy Menstrual Bleeding Using Systems Biology Approaches

Wang C-Y. et al, (2022), REPRODUCTIVE SCIENCES, 29, 204 - 204

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