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Publications

Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor.

O'Brien DP. et al, (2025), J Proteome Res, 24, 479 - 490

Crystal structure of Fatty Acid Thioesterase A bound by 129 fragments provides diverse development opportunities

Kot E. et al, (2024)

MITOCHONDRIAL DYSFUNCTION IN NEUROSCIENCE: RECENT DEVELOPMENTS IN USP30 INHIBITORS

Worm K. et al, (2024), Medicinal Chemistry Reviews, 37 - 58

Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor

O’Brien DP. et al, (2024)

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides.

O'Brien DP. et al, (2023), Mol Cell Proteomics, 22

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

O’Brien DP. et al, (2022)

USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.

Rusilowicz-Jones EV. et al, (2020), Life Sci Alliance, 3

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