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Oxford ramps up COVID-19 testing capability

The University of Oxford has joined forces with Thermo Fisher Scientific, the world leader in serving science, to ramp up the university’s capacity to deliver COVID-19 testing data.

Structure of the helicase core of Werner helicase, a key target in microsatellite instability cancers (new paper published)

Loss of WRN, a DNA repair helicase, was identified as a strong vulnerability of microsatellite instable (MSI) cancers, making WRN a promising drug target.

TBXT: A new Target Enabling package for rare disease

The Target Enabling Packages (TEPs) Programme continues to elucidate and enable novel targets for drug development.

Structural Biology identifies new information to accelerate structure-based drug design against Covid-19

A new paper in Nature Communications outlines how an international research team has identified potential ways forward to rapidly design improved and more potent compounds in the fight against COVID-19.

Wyatt Yue awarded 2021 Harrington UK Rare Disease Scholar Awards

The Harrington Discovery Institute in the US has announced five winners of its inaugural UK Rare Disease Scholar Award competition.

CMD begins project to revolutionise drug discovery using AI

The Centre for Medicines Discovery and King Abdulaziz University (KAU) have launched a major collaboration to accelerate medicines discovery using AI technologies, for diseases with unmet need, including rare diseases and cardio-metabolic diseases.

COVID Moonshot – aiming to develop novel small molecule inhibitors targeting SARS-CoV-2

A large collaborative initiative to contribute to the global anti- COVID-19 effort.

Crystal structure of SARS-CoV-2 nsp13 (helicase)

Joseph Newman has solved a crystal structure of the viral helicase at 1.94 Angstrom resolution (PDB: 6ZSL).

TargetDB: summarising target information

TargetDB is a tool that aggregates public information available on given target(s) (links to disease, safety, 3D structures, ligandability, novelty, etc.) and assembles it in an easy to read output ready for the researcher to analyse.

The Centre for Medicines Discovery is launched

The CMD brings together expertise and capabilities in drug discovery across the Nuffield Department of Medicine.

Work starts on international EUbOPEN chemogenomics effort

The project will last five years and deliver high quality chemical tools that can be used to investigate the biology of disease and discover new targets for drug discovery