Lizbé Koekemoer
Protein Crystallography SRF Coordinator
Key publications
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Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors
Journal article
Boby ML. et al, (2020)
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A selection of Golden Gate vectors to simplify recombinant protein production inEscherichia coli
Preprint
Fairhead M. et al, (2024)
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Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity.
Journal article
Govender P. et al, (2022), J Med Chem
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The low-cost Shifter microscope stage transforms the speed and robustness of protein crystal harvesting.
Journal article
Wright ND. et al, (2021), Acta Crystallogr D Struct Biol, 77, 62 - 74
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The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity.
Journal article
Mostert KJ. et al, (2021), ACS Chem Biol
Recent publications
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A selection of Golden Gate vectors to simplify recombinant protein production inEscherichia coli
Preprint
Fairhead M. et al, (2024)
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Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.
Journal article
Boby ML. et al, (2023), Science, 382
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Turning high-throughput structural biology into predictive inhibitor design.
Journal article
Saar KL. et al, (2023), Proc Natl Acad Sci U S A, 120
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Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts
Preprint
Ye M. et al, (2022)
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Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity.
Journal article
Govender P. et al, (2022), J Med Chem