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Publications

Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.

Boby ML. et al, (2023), Science, 382

Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts

Ye M. et al, (2022)

Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity.

Govender P. et al, (2022), J Med Chem

Expanding the Repertoire of Low-Molecular-Weight Pentafluorosulfanyl-Substituted Scaffolds.

Jose A. et al, (2022), ChemMedChem

The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity.

Mostert KJ. et al, (2021), ACS Chem Biol

The low-cost Shifter microscope stage transforms the speed and robustness of protein crystal harvesting.

Wright ND. et al, (2021), Acta Crystallogr D Struct Biol, 77, 62 - 74

Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors

Boby ML. et al, (2020)