Contact information
Research groups
Michael Lowe
Research Assistant - Organelle Biology and High-throughput Screening
Michael graduated with a BSc in Natural Sciences from the University of Bath in 2021. This included a year in industry where he worked at the Alzheimer’s Research UK UCL Drug Discovery Institute in London. Here he was part of the Neuroinflammation team, characterising a range of model systems for their suitability for upcoming screening campaigns and performed assay development over a range of platforms including the InCucyte and Operetta. He then completed an MSc in Neuroscience at King’s College London in 2022. His research project here was to develop a full phenotypic assay workflow using iPSCs from culture to automated analysis which was suitable for hit compound screening.
He is now part of the Organelle Biology team at the ARUK Oxford Drug Discovery Institute where he leads a phenotypic cell-based high-throughput screen assessing calcium flux. To date this project has screened over 100,000 small molecules and he is progressing these hits through the hit-to-lead screening cascade utilising a range of platforms including the FLIPR and Opera Phenix.