Contact information
Research groups
Websites
-
Marsden Group | Research Informatics
Research Group, Kennedy Institute
-
CMD Research Informatics
Research group
Brian Marsden
BA (Cantab), MA (Cantab), D.Phil. (Oxon)
Associate Professor, Research Informatics; Associate Head of Medical Sciences Division - Digital and Information
- Chair of University Research Computing Board
Brian is responsible for driving research informatics and research computing capabilities at the Kennedy Institute and the Centre for Medicines Discovery.
After completing a D.Phil. within the Iain Campbell lab at the University of Oxford, Brian was awarded a Wellcome Trust Prize Fellowship which he spent at the Abagyan lab at the Scripps Research Institute, La Jolla, USA, devising novel methods for proteins structure superimposition and also implementing high performance compute and storage clusters. He then worked as part of the Computational Chemistry group at BioFocus PLC before settling down at the SGC in Oxford and now the Centre for Medicines Discovery where he continues to be responsible for all aspects of Informatics, IT and structural bioinformatics. He has a particular interest in the development of novel data capture and visualisation methods for structural and chemical biology data.
Since 2013, Brian has split his time with the Kennedy Institute where he and his team are responsible for the provision of IT capabilities as well as effective data management platforms to support the broad range of science within the Institute.
Recent publications
-
MolSnapper: Conditioning Diffusion for Structure-Based Drug Design.
Journal article
Ziv Y. et al, (2025), J Chem Inf Model
-
Fragmenstein: predicting protein-ligand structures of compounds derived from known crystallographic fragment hits using a strict conserved-binding-based methodology.
Journal article
Ferla MP. et al, (2025), J Cheminform, 17
-
EEFSEC deficiency: A selenopathy with early-onset neurodegeneration.
Journal article
Laugwitz L. et al, (2025), Am J Hum Genet, 112, 168 - 180
-
Toward target 2035: EUbOPEN - a public-private partnership to enable & unlock biology in the open.
Journal article
Tredup C. et al, (2024), RSC Med Chem
-
Early regional lymph node activation drives influenza vaccine responses in an ancestrally diverse cohort
Preprint
Siu JHY. et al, (2024)