Our group uses chemical biology to uncover new principles of cellular regulation and identify points of intervention for future medicines. By designing small molecules that probe biological systems, we can reveal hidden mechanisms - and ultimately, develop strategies to restore cellular balance in disease.
Probing Biology with Small Molecules for Drug Target Discovery
To identify, explore, and validate new targets, the Huber Laboratory integrates a wide range of discovery approaches - including small-molecule and phenotypic screening, biochemical and structural biology, protein–protein interaction and chemical proteomics, medicinal chemistry, and genetic perturbation methods such as RNAi and CRISPR-based editing.
By combining these complementary techniques, we aim to generate high-quality chemical probes that illuminate fundamental biology and provide starting points for drug discovery.
Our team
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Kilian Huber
Associate Professor
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Jesper Hansen
Postdoctoral Scientist
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Haozhe Xiao
DPhil Student
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Yusi Liu
Postdoctoral Scientist
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Alice Page
DPhil Student
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Alejandro Gonzalez Orta
Research Assistant - Cellular Assay Development & High-Throughput Screening
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Frederik Feeser
Visitor
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Yanzhi Guo
DPhil Student
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Vittorio Katis
TREAT-AD Team Leader
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Michael Miller
Post Doctoral Research Scientist
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Lukas Scheibelberger
Postdoctoral Research Scientist - Medicinal Chemistry
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Philipp Dirmeier
DPhil Student
