Contact information
Michael Ellis
Research Assistant Neuroinflammation
I am working alongside Dr Irina Stefana to investigate the mechanisms underlying the loss of pancreatic beta-cell function seen in type 1 diabetes. The primary focus of this project is investigating the role of the microtubule-associated protein Tau, alongside the various phosphorylated variants, attempting to determine the mechanisms driving this beta-cell failure.
Originally from York, I completed a BSc (Hons) in Medical Sciences and an MSc in Molecular Medicine, both from the University of Leeds. During this time, I investigated the epigenetic regulation of drug-resistant chronic myeloid leukaemia and the associated mechanisms. I joined the DIL Group in August 2019 as a Laboratory Technician working within the Sample Processing Team. I was in this position for nine months before joining the Ludwig Institute for Cancer Research in April 2020 as a Research Assistant. In this position, I investigated how p53 influences the development of pancreatic cancer using a murine model. Finally, I re-joined the Todd-Wicker Group in April 2021 as a Research Assistant.
Recent publications
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Identification of high-performing antibodies for the reliable detection of Tau proteoforms by Western blotting and immunohistochemistry.
Journal article
Ellis MJ. et al, (2024), Acta Neuropathol, 147