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Contact information

Email
tryfon.zarganis-tzitzikas@cmd.ox.ac.uk

Research groups

The Alzheimer’s Research UK Oxford Drug Discovery Institute (ODDI)

Tryfon Zarganis-Tzitzikas

Head of Chemistry, Alzheimer’s Research UK Oxford Drug Discovery Institute

Recent publications

Chemical probes for Alzheimer's disease targets.

Aiken SG. et al, (2026), Essays Biochem

Ugi-Tetrazole-Derived α‑Aminomethyl Scaffolds Reveal Unexpected Binding Modes in SARS-CoV‑2 3CLpro.

van der Straat R. et al, (2026), ACS Med Chem Lett, 17, 856 - 865

A patent review of peptidylarginine deiminase 4 (PAD4) inhibitors (2014-present).

Aiken SG. et al, (2025), Expert Opin Ther Pat, 35, 611 - 621

Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor.

O'Brien DP. et al, (2025), J Proteome Res, 24, 479 - 490

Covalent Inhibitors of S100A4 Block the Formation of a Pro-Metastasis Non-Muscle Myosin 2A Complex.

Giroud C. et al, (2024), J Med Chem, 67, 18943 - 18956

More publications