The Centre for Medicines Discovery aims to catalyse the discovery
and development of new medicines for patients.
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Publications
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Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex.
Journal article
Damianou A. et al, (2024), Life Sci Alliance, 7
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The pRb/RBL2-E2F1/4-GCN5 axis regulates cancer stem cell formation and G0 phase entry/exit by paracrine mechanisms.
Journal article
Chang C-H. et al, (2024), Nat Commun, 15
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Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia.
Journal article
Liang Z. et al, (2024), Cell Rep, 43