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Contact information

Email
zhuoyao.chen@cmd.ox.ac.uk

ORCID
https://orcid.org/0000-0003-4201-4649

Research groups

Growth Factor Signalling and Ubiquitination

Zhuoyao Chen

Senior Scientist

E3 ligases in cancer biology

Recent publications

Ubiquitin E3 ligase KLHL6 brings exhausted T-cells back into action.

Chen Z. et al, (2026), Immun Inflamm, 2

Structural mimicry of UM171 and neomorphic cancer mutants co-opts E3 ligase KBTBD4 for HDAC1/2 recruitment.

Chen Z. et al, (2025), Nat Commun, 16

Relationship between HLA genetic variations, COVID-19 vaccine antibody response, and risk of breakthrough outcomes.

Xie J. et al, (2024), Nat Commun, 15

HLA Alleles, COVID-19 Vaccine Antibody Response and Real-World Breakthrough Outcomes

Prieto-Alhambra D. et al, (2023)

Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation.

Chen Z. et al, (2022), Cell Death Differ, 29, 1955 - 1969

More publications