Joseph Newman
Postdoctoral Scientist
Recent publications
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FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency.
Journal article
Rota IA. et al, (2021), Sci Adv, 7
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A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family.
Journal article
Baddock HT. et al, (2021), Nucleic Acids Res, 49, 9294 - 9309
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Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition.
Journal article
Yosaatmadja Y. et al, (2021), Nucleic Acids Res, 49, 9310 - 9326
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Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase.
Journal article
Newman JA. et al, (2021), Nat Commun, 12
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SPRTN protease-cleaved MRE11 decreases DNA repair and radiosensitises cancer cells.
Journal article
Na J. et al, (2021), Cell Death Dis, 12