Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics.
Acevedo-Rocha CG. et al, (2021), Nat Commun, 12
Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking.
Schuller M. et al, (2020), bioRxiv
Non-coding variants upstream of MEF2C cause severe developmental disorder through three distinct loss-of-function mechanisms
Wright C. et al, (2020)