Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Publications

Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor.

O'Brien DP. et al, (2025), J Proteome Res, 24, 479 - 490

USP30 inhibition improves mitochondrial health through both PINK1-dependent and independent mechanisms

Williamson MG. et al, (2025)

Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor

O’Brien DP. et al, (2024)

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides.

O'Brien DP. et al, (2023), Mol Cell Proteomics, 22

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

O’Brien DP. et al, (2022)

USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.

Rusilowicz-Jones EV. et al, (2020), Life Sci Alliance, 3

A novel USP30 inhibitor recapitulates genetic loss of USP30 and sets the trigger for PINK1-PARKIN amplification of mitochondrial ubiquitylation

Rusilowicz-Jones E. et al, (2020)

Pre- and postoperative headache in patients with meningioma.

Guenther F. et al, (2019), Cephalalgia, 39, 533 - 543

Impaired Nociception in the Diabetic Ins2+/Akita Mouse.

Vastani N. et al, (2018), Diabetes, 67, 1650 - 1662

Complex reinnervation pattern after unilateral renal denervation in rats.

Rodionova K. et al, (2016), Am J Physiol Regul Integr Comp Physiol, 310, R806 - R818

Include forthcoming?