A general and mild two-step procedure for the synthesis of aryl and heteroaryl sulfonamides from the corresponding iodides
Ho DKH., Chan L., Hooper A., Brennan PE.
A mild two-step preparation of aryl and heteroaryl sulfonyl chlorides and sulfonamides from their corresponding iodides is developed. Acid labile functionalities are shown to be stable under both the copper-catalysed coupling and the subsequent oxidative chlorination. © 2010 American Chemical Society.