Identification of Tyr58 as the proton donor in the aspartate-alpha-decarboxylase reaction.
Saldanha SA., Birch LM., Webb ME., Nabbs BK., von Delft F., Smith AG., Abell C.
The decarboxylation of L-aspartate by E. coli L-aspartate-alpha-decarboxylase (ADC) is shown to occur with retention of configuration; analysis of the protein structure identifies Tyr58 as the proton donor in the decarboxylation mechanism.