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<jats:title>Abstract</jats:title><jats:p>Thermal profiling (TP) has emerged as a promising experimental methodology for elucidating the molecular targets of drugs and metabolites on a proteome-wide scale. Here, we present the Thermal Profiling Meltome Analysis Program (TP-MAP) software package for the analysis and ranking of 1D and 2D thermal profiling datasets. TP-MAP provides a user-friendly interface to quickly identify hit candidates and further explore targets of interest via intersection and crosslinking to public databases.</jats:p>

Original publication

DOI

10.1101/2021.02.22.432361

Type

Journal article

Publisher

Cold Spring Harbor Laboratory

Publication Date

23/02/2021