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Publications

Carbamoyl fluorides as serine hydrolase inhibitors: a case study on FphI from Staphylococcus aureus

Randall G. et al, (2026), Bioorganic Chemistry, 176, 109834 - 109834

Urine Recirculation During Normothermic Kidney Preservation Improves Energy Balance Involving the Urea and Citric Acid Cycles.

Weissenbacher A. et al, (2026), Transplant Direct, 12

Structural insights into cobalamin loading and reactivation of human methionine synthase.

Ferreira DSM. et al, (2026), Nat Commun

An Explainable Deep Learning Framework for Imaging Genetics: Deriving Brain-Genotype Scores From MRI to Link Genetic Variation, Brain Structure, and Cognition

Alhasani KT. et al, (2026)

Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome.

Koprulu M. et al, (2026), Cell

Targeting Activin Receptor-like Kinase 2 Using Heterobifunctional Protein Degraders.

Webb DT. et al, (2026), J Med Chem

DNA-induced conformational changes in SPRTN relieve its auto-inhibitory effect on protease activity.

Song W. et al, (2026), bioRxiv

Discovery and Characterization of a Nonacidic Small-Molecule Inhibitor of the Sodium-Coupled Dicarboxylate Transporter NaCT.

Quigley A. et al, (2026), J Med Chem

Pleural fluid neutrophil extracellular traps are associated with disease severity and risk of one-year mortality in pleural infection. An observational, international, multicohort study (TORPIDS-3).

Chu JY. et al, (2026), Eur Respir J

K63-linked ubiquitylation of S2P-RNAPII regulates transcription in a DNAPK inter-dependent manner in response to double-strand breaks.

Pantazi V. et al, (2026), Nucleic Acids Res, 54

Targeted Intracellular Delivery of Amino Acids to Trophoblast Cells Reveals Proteomic Signatures of Cellular Utilisation

Mazey E. et al, (2026), Biomolecules, 16, 628 - 628

SPNS2 exports sphingosine-1-phosphate and imports glucose.

Weigel C. et al, (2026), Nat Commun

KDM3A catalyses the oxidation of acetyl-lysine to hydroxyacetyl-lysine on histone H3K9.

Belle R. et al, (2026), Nat Chem

iNOS modulates inflammatory responses in an NO-independent manner through direct interaction with IRG1 in mitochondria.

Diotallevi M. et al, (2026), Nat Metab

Ugi-Tetrazole-Derived α‑Aminomethyl Scaffolds Reveal Unexpected Binding Modes in SARS-CoV‑2 3CLpro.

van der Straat R. et al, (2026), ACS Med Chem Lett, 17, 856 - 865

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