The changing face of UK academic drug screening in the past decade
Journal article
Baronio R. and Ebner D., (2026), Nature Reviews Drug Discovery
AI-assisted fragment-based drug discovery of SARS-CoV-2 macrodomain binders validated by NMR and X-ray crystallography.
Journal article
Aledavood E. et al, (2026), Commun Chem
Functional role of a structural water in the elevator domain of dicarboxylate transporter VcINDY
Journal article
Daab A. et al, (2026), PNAS Nexus
Multiomic profiling of responses to clinical and novel bisphosphonates reveals extraskeletal effects on ageing related signatures.
Journal article
Lu J. et al, (2026), Signal Transduct Target Ther, 11
Structures of the human sodium-citrate cotransporter NaCT with and without substrates
Preprint
Sauer DB. et al, (2026)
Molecular Solution to the Paradox of Ancient Brain Preservation.
Journal article
Morton-Hayward A. et al, (2026), J Proteome Res
CDIN1-Codanin-1 complex defective in congenital dyserythropoietic anaemia type I is an RNA nuclease.
Conference paper
Brolih S. et al, (2026), Nat Commun
Towards light-coupled sample preparation for time-resolved cryoEM studies.
Journal article
Hadjidemetriou K. et al, (2026), IUCrJ, 13, 395 - 408
Carbamoyl fluorides as serine hydrolase inhibitors: a case study on FphI from Staphylococcus aureus
Journal article
Randall G. et al, (2026), Bioorganic Chemistry, 176, 109834 - 109834
Targeted Protein Degradation of NUDT5 Dissociates Catalytic Inhibition from Protein Loss in 6-Thioguanine Response.
Journal article
Marques A-SMC. et al, (2026), Nat Commun
ChatMDV: Reducing Technical Barriers in Bioinformatics Analysis using Large Language Models.
Journal article
Kiourlappou M. et al, (2026), Gigascience
USP24 is a cross-reactive DUB targeting MOV10 to regulate IFN-I production.
Journal article
Mukhopadhyay R. et al, (2026), Nat Commun
A comprehensive pharmacological survey across heterogeneous patient-derived glioblastoma stem cell models
Journal article
Elliott RJR. et al, (2026), Iscience, 29
Proteomic signatures of mitochondrial dysfunction associated with atrial fibrillation in goats.
Journal article
Ayagama T. et al, (2026), Sci Rep
PAD4 deletion in synovial macrophages exacerbates pathology in inflammatory arthritis.
Journal article
Mayr MG. et al, (2026), Res Sq
