Research groups
Zhuoyao Chen
Senior Scientist
E3 ligases in cancer biology
Recent publications
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Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation.
Journal article
Chen Z. et al, (2022), Cell Death Differ, 29, 1955 - 1969
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Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12.
Journal article
Chen Z. et al, (2020), Open Biol, 10
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Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12
Journal article
Chen Z. et al, (2020)
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Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase.
Journal article
Chen Z. et al, (2019), Structure, 27, 1395 - 1404.e4
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The Arabidopsis RING-Type E3 Ligase TEAR1 Controls Leaf Development by Targeting the TIE1 Transcriptional Repressor for Degradation.
Journal article
Zhang J. et al, (2017), Plant Cell, 29, 243 - 259