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Theodosios Kyriakou
Senior Programme Manager
Theodosios Kyriakou is a Senior Programme Manager and Translational Scientist in the Centre for Medicines Discovery. He has a background in Genomics and Molecular Genetics and extensive experience in research of complex diseases. He has received his PhD from the University of Warwick after graduate and postgraduate studies at the University of Glasgow. His research interests focused on functional investigation of genes associated with cardiovascular disease and while at the Oxford Genomics Centre was the lead project manager for long range sequencing.
Theodosios joined the BRC team in 2024 as a Translational Scientist and Senior Programme Manager and is currently working on a range of projects developing novel drug targets in a variety of therapeutic areas with a primary focus on rare diseases. Theo is also a Senior lecturer at Keble College teaching Genetics to undergraduates studying Medicine and Biomedical Sciences.
Recent publications
Micro-capture-C in vessel wall cell types identifies mechanisms underlying coronary artery disease susceptibility loci
Journal article
Baxter M. et al, (2024), EUROPEAN HEART JOURNAL, 45
PHACTR1 modulates vascular compliance but not endothelial function: a translational study.
Journal article
Wood A. et al, (2023), Cardiovasc Res, 119, 599 - 610
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants.
Journal article
Aragam KG. et al, (2022), Nat Genet, 54, 1803 - 1815
A key role for the novel coronary artery disease gene JCAD in atherosclerosis via shear stress mechanotransduction.
Journal article
Douglas G. et al, (2020), Cardiovasc Res, 116, 1863 - 1874
Differential Gene Expression in Macrophages From Human Atherosclerotic Plaques Shows Convergence on Pathways Implicated by Genome-Wide Association Study Risk Variants.
Journal article
Chai JT. et al, (2018), Arterioscler Thromb Vasc Biol, 38, 2718 - 2730
