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Publications

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides.

O'Brien DP. et al, (2023), Mol Cell Proteomics, 22

Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2

Bradshaw WJ. et al, (2023)

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

O’Brien DP. et al, (2022)

USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.

Rusilowicz-Jones EV. et al, (2020), Life Sci Alliance, 3

A novel USP30 inhibitor recapitulates genetic loss of USP30 and sets the trigger for PINK1-PARKIN amplification of mitochondrial ubiquitylation

Rusilowicz-Jones E. et al, (2020)

Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail.

Wang J. et al, (2020), Sci Rep, 10

Complete NMR chemical shift assignments of odorant binding protein 22 from the yellow fever mosquito, Aedes aegypti, bound to arachidonic acid.

Jones DNM. et al, (2019), Biomol NMR Assign, 13, 187 - 193

Interactions of Anopheles gambiae odorant-binding proteins with a human-derived repellent: implications for the mode of action of n,n-diethyl-3-methylbenzamide (DEET).

Murphy EJ. et al, (2013), J Biol Chem, 288, 4475 - 4485

New insights into the mechanism of odorant detection by the malaria-transmitting mosquito Anopheles gambiae.

Davrazou F. et al, (2011), J Biol Chem, 286, 34175 - 34183

CO binding and ligand discrimination in human myeloperoxidase.

Murphy EJ. et al, (2010), Biochemistry, 49, 2150 - 2158

Fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D1.

Aubry C. et al, (2009), Bioorg Med Chem, 17, 6073 - 6084