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Publications

The binding and mechanism of a positive allosteric modulator of Kv3 channels.

Liang Q. et al, (2024), Nat Commun, 15

Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays.

van Veggel L. et al, (2024), ACS Chem Neurosci

High-Throughput Expression and Purification of Human Solute Carriers for Structural and Biochemical Studies.

Raturi S. et al, (2023), J Vis Exp

The solute carrier SPNS2 recruits PI(4,5)P2 to synergistically regulate transport of sphingosine-1-phosphate.

Tang H. et al, (2023), Mol Cell, 83, 2739 - 2752.e5

Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2

Li HZ. et al, (2023)

Elevator mechanism dynamics in a sodium-coupled dicarboxylate transporter

Kinz-Thompson C. et al, (2023), PROTEIN SCIENCE, 32

Structural basis of ion - substrate coupling in the Na+-dependent dicarboxylate transporter VcINDY.

Sauer DB. et al, (2022), Nat Commun, 13

Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus.

Brawley DN. et al, (2022), Nat Chem Biol

Elevator mechanism dynamics in a sodium-coupled dicarboxylate transporter

Kinz-Thompson CD. et al, (2022)

The ups and downs of elevator-type di-/tricarboxylate membrane transporters.

Sauer DB. et al, (2021), FEBS J

Structure and inhibition mechanism of the human citrate transporter NaCT.

Sauer DB. et al, (2021), Nature, 591, 157 - 161

Structure and inhibition mechanism of the human citrate transporter NaCT

Sauer, D. et al, (2021), Nature, 591, 157 - 161

Structural basis for the reaction cycle of DASS dicarboxylate transporters.

Sauer DB. et al, (2020), Elife, 9

Structural basis for the reaction cycle of DASS dicarboxylate transporters

Sauer, D. et al, (2020), eLife, 9

Predicting the optimal growth temperatures of prokaryotes using only genome derived features

Sauer, D. and Wang, D., (2019), Bioinformatics, 35, 3224 - 3231

Prediction of Optimal Growth Temperature using only Genome Derived Features

Sauer D. and Wang D-N., (2018)

Rapid Bioinformatic Identification of Thermostabilizing Mutations.

Sauer DB. et al, (2015), Biophys J, 109, 1420 - 1428

Rapid Bioinformatic Identification of Thermostabilizing Mutations

Sauer, D. et al, (2015), Biophysical Journal, 109, 1420 - 1428

The conserved potassium channel filter can have distinct ion binding profiles: structural analysis of rubidium, cesium, and barium binding in NaK2K.

Lam YL. et al, (2014), J Gen Physiol, 144, 181 - 192

The conserved potassium channel filter can have distinct ion binding profiles: Structural analysis of rubidium, cesium, and barium binding in NaK2K

Lam, Y. et al, (2014), Journal of General Physiology, 144, 181 - 192

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