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Publications

Amino acid and viral binding by the high-affinity Cationic Amino acid Transporter 1 (CAT1) from Mus musculus

Sauer D. et al, (2024)

Pho pictures provide powerful perspectives of phosphate importing proteins.

Speedman D. and Sauer DB., (2024), Structure, 32, 849 - 850

Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2.

Li HZ. et al, (2024), Nat Commun, 15

Protein binder toolbox for studies of solute carrier transporters.

Gelová Z. et al, (2024), J Mol Biol

Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays.

van Veggel L. et al, (2024), ACS Chem Neurosci, 15, 1424 - 1431

The binding and mechanism of a positive allosteric modulator of Kv3 channels.

Liang Q. et al, (2024), Nat Commun, 15

Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily.

Digles D. et al, (2024), Front Pharmacol, 15

Di-Gluebodies as covalently-rigidified, modular protein assemblies enable simultaneous determination of high-resolution, low-size, cryo-EM structures

Yi G. et al, (2024)

Structural basis of the mechanism and inhibition of a human ceramide synthase

Pascoa TC. et al, (2023)

Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2

Sauer D. et al, (2023)

High-Throughput Expression and Purification of Human Solute Carriers for Structural and Biochemical Studies.

Raturi S. et al, (2023), J Vis Exp

The solute carrier SPNS2 recruits PI(4,5)P2 to synergistically regulate transport of sphingosine-1-phosphate.

Tang H. et al, (2023), Mol Cell, 83, 2739 - 2752.e5

Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2

Li HZ. et al, (2023)

Elevator mechanism dynamics in a sodium-coupled dicarboxylate transporter

Kinz-Thompson C. et al, (2023), PROTEIN SCIENCE, 32

Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus.

Brawley DN. et al, (2022), Nat Chem Biol, 18, 706 - 712

Structural basis of ion - substrate coupling in the Na+-dependent dicarboxylate transporter VcINDY.

Sauer DB. et al, (2022), Nat Commun, 13

The ups and downs of elevator-type di-/tricarboxylate membrane transporters.

Sauer DB. et al, (2022), FEBS J, 289, 1515 - 1523

Elevator mechanism dynamics in a sodium-coupled dicarboxylate transporter

Kinz-Thompson CD. et al, (2022)

Structure and inhibition mechanism of the human citrate transporter NaCT.

Sauer DB. et al, (2021), Nature, 591, 157 - 161

Structure and inhibition mechanism of the human citrate transporter NaCT

Sauer, D. et al, (2021), Nature, 591, 157 - 161

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