Beth MacLean
Researcher in Laboratory Engineering and CryoEM
Recent publications
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Crystallographic Fragment Screen of Coxsackievirus A16 2A Protease identifies new opportunities for the development of broad-spectrum anti-enterovirals.
Preprint
Lithgo RM. et al, (2024)
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Crystallographic fragment screen of Enterovirus D68 3C protease and iterative design of lead-like compounds using structure-guided expansions
Preprint
Lithgo R. et al, (2024)
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Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.
Journal article
Boby ML. et al, (2023), Science, 382
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Turning high-throughput structural biology into predictive inhibitor design.
Journal article
Saar KL. et al, (2023), Proc Natl Acad Sci U S A, 120
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Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive close contacts
Preprint
Ye M. et al, (2022)