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Search results (18)

« Back to Publications

Tracking E2-specific substrates.

Jones HBL. et al, (2025), Nat Chem Biol, 21, 976 - 977

Integrative proximal-ubiquitomics profiling for deubiquitinase substrate discovery applied to USP30.

Damianou A. et al, (2025), Cell Chem Biol, 32, 736 - 751.e8

Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor.

O'Brien DP. et al, (2025), J Proteome Res, 24, 479 - 490

Protocol to profile spatially resolved NLRP3 inflammasome complexes using APEX2-based proximity labeling.

Liang Z. et al, (2024), STAR Protoc, 5

Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor

O’Brien DP. et al, (2024)

Deubiquitinases in muscle physiology and disorders.

Olie CS. et al, (2024), Biochem Soc Trans, 52, 1085 - 1098

Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1.

Imhoff RD. et al, (2024), J Med Chem, 67, 4496 - 4524

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides.

O'Brien DP. et al, (2023), Mol Cell Proteomics, 22

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

O’Brien DP. et al, (2022)

ABPP-HT*-Deep Meets Fast for Activity-Based Profiling of Deubiquitylating Enzymes Using Advanced DIA Mass Spectrometry Methods.

Jones HBL. et al, (2022), Int J Mol Sci, 23

Chemical Mapping Exposes the Importance of Active Site Interactions in Governing the Temperature Dependence of Enzyme Turnover.

Winter SD. et al, (2021), ACS Catal, 11, 14854 - 14863

Sensing Enzyme Activation Heat Capacity at the Single-Molecule Level Using Gold-Nanorod-Based Optical Whispering Gallery Modes.

Subramanian S. et al, (2021), ACS Appl Nano Mater, 4, 4576 - 4583

ABPP-HT - High-Throughput Activity-Based Profiling of Deubiquitylating Enzyme Inhibitors in a Cellular Context.

Jones HBL. et al, (2021), Front Chem, 9

Monoclonal antibody stability can be usefully monitored using the excitation-energy-dependent fluorescence edge-shift.

Knight MJ. et al, (2020), Biochem J, 477, 3599 - 3612

Exposing the Interplay Between Enzyme Turnover, Protein Dynamics, and the Membrane Environment in Monoamine Oxidase B.

Jones HBL. et al, (2019), Biochemistry, 58, 2362 - 2372

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