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Search results (29)

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Validating novel neurodegenerative targets for future dementia therapeutics.

Murphy E., (2026), Expert Opin Ther Targets, 30, 1 - 3

SHIP1 regulates TREM2 signalling and macrophage functions in a hiPSC-derived model

Martin CS. et al, (2025)

ob ABPP-HT*: A Precision-Engineered Activity Proteomics Pipeline for the Streamlined Discovery of Deubiquitinase Inhibitors

Jones HBL. et al, (2025)

Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor.

O'Brien DP. et al, (2025), J Proteome Res, 24, 479 - 490

USP30 inhibition improves mitochondrial health through both PINK1-dependent and independent mechanisms

Williamson MG. et al, (2025)

Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor

O’Brien DP. et al, (2024)

Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2.

Bradshaw WJ. et al, (2024), Structure, 32, 453 - 466.e6

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides.

O'Brien DP. et al, (2023), Mol Cell Proteomics, 22

Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2

Bradshaw WJ. et al, (2023)

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

O’Brien DP. et al, (2022)

USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.

Rusilowicz-Jones EV. et al, (2020), Life Sci Alliance, 3

A novel USP30 inhibitor recapitulates genetic loss of USP30 and sets the trigger for PINK1-PARKIN amplification of mitochondrial ubiquitylation

Rusilowicz-Jones E. et al, (2020)

Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail.

Wang J. et al, (2020), Sci Rep, 10

Correction to: Complete NMR chemical shift assignments of odorant binding protein 22 from the yellow fever mosquito, Aedes aegypti, bound to arachidonic acid.

Jones DNM. et al, (2019), Biomol NMR Assign, 13

Complete NMR chemical shift assignments of odorant binding protein 22 from the yellow fever mosquito, Aedes aegypti, bound to arachidonic acid.

Jones DNM. et al, (2019), Biomol NMR Assign, 13, 187 - 193

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