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Search results (23)

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RaPID discovery of cell-permeable helical peptide inhibitors con-taining cyclic β-amino acids against SARS-CoV-2 main protease.

Kawai M. et al, (2025), RSC Chem Biol, 6, 1089 - 1099

Cyclic β2,3-amino acids improve the serum stability of macrocyclic peptide inhibitors targeting the SARS-CoV-2 main protease.

Miura T. et al, (2024), Bull Chem Soc Jpn, 97

Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.

Boby ML. et al, (2023), Science, 382

In vitro selection of macrocyclic peptide inhibitors containing cyclic γ2,4-amino acids targeting the SARS-CoV-2 main protease.

Miura T. et al, (2023), Nat Chem, 15, 998 - 1005

Accelerating drug target inhibitor discovery with a deep generative foundation model.

Chenthamarakshan V. et al, (2023), Sci Adv, 9

Turning high-throughput structural biology into predictive inhibitor design.

Saar KL. et al, (2023), Proc Natl Acad Sci U S A, 120

Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine.

Brewitz L. et al, (2023), J Med Chem, 66, 2663 - 2680

Penicillin Derivatives Inhibit the SARS-CoV-2 Main Protease by Reaction with Its Nucleophilic Cysteine.

Malla TR. et al, (2022), J Med Chem, 65, 7682 - 7696

Mass Spectrometric Assays Reveal Discrepancies in Inhibition Profiles for the SARS-CoV-2 Papain-Like Protease.

Brewitz L. et al, (2022), ChemMedChem, 17

Expanding the Repertoire of Low-Molecular-Weight Pentafluorosulfanyl-Substituted Scaffolds.

Jose A. et al, (2022), ChemMedChem, 17

Studies on the Reactions of Biapenem with VIM Metallo β-Lactamases and the Serine β-Lactamase KPC-2.

Lucic A. et al, (2022), Antibiotics (Basel), 11

Structure-Activity Studies Reveal Scope for Optimisation of Ebselen-Type Inhibition of SARS-CoV-2 Main Protease.

Thun-Hohenstein STD. et al, (2022), ChemMedChem, 17

Discovery of SARS-CoV-2 Mpro peptide inhibitors from modelling substrate and ligand binding.

Chan HTH. et al, (2021), Chem Sci, 12, 13686 - 13703

Publisher Correction: Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19.

Redhead MA. et al, (2021), Sci Rep, 11

Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19.

Redhead MA. et al, (2021), Sci Rep, 11

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