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Search results (23)

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Combined crystallographic fragment screening and deep mutational scanning enable discovery of Zika virus NS2B-NS3 protease inhibitors.

Ni X. et al, (2025), Nat Commun, 16

High-throughput crystallographic fragment screening of Zika virus NS3 Helicase.

Godoy AS. et al, (2025)

Binding-Site Purification of Actives (B-SPA) Enables Efficient Large-Scale Progression of Fragment Hits by Combining Multi-Step Array Synthesis With HT Crystallography.

Grosjean H. et al, (2025), Angew Chem Int Ed Engl, 64

Crystallographic fragment screening and deep mutational scanning of Zika virus NS2B-NS3 protease enable development of resistance-resilient inhibitors.

Ni X. et al, (2025)

Crystallographic fragment screening and deep mutational scanning of Zika virus NS2B-NS3 protease enable development of resistance-resilient inhibitors.

von Delft F. et al, (2025), Res Sq

Heterologous production, purification and crystallization of 24C-sterol methyltransferase from Candida albicans

Mpontshane NS. et al, (2025)

Dengue 2 NS2B-NS3 protease binding assay for compound screen using grating-coupled interferometry v1

Capkin E. et al, (2025)

Accelerating Drug Discovery With High-Throughput Crystallographic Fragment Screening and Structural Enablement

Fearon D. et al, (2025), Applied Research, 4

Crystal structure of Fatty Acid Thioesterase A bound by 129 fragments provides diverse development opportunities

Kot E. et al, (2024)

Zika virus NS2B-NS3 protease binding assay for compound screen using grating-coupled interferometry v1

Capkin E. et al, (2024)

Identifying novel chemical matter against the Chikungunya virus nsP3 macrodomain through crystallographic fragment screening.

Aschenbrenner JC. et al, (2024)

Crystallographic Fragment Screen of Coxsackievirus A16 2A Protease identifies new opportunities for the development of broad-spectrum anti-enterovirals.

Lithgo RM. et al, (2024)

A selection of Golden Gate vectors to simplify recombinant protein production in Escherichia coli

Fairhead M. et al, (2024)

Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.

Boby ML. et al, (2023), Science, 382

Turning high-throughput structural biology into predictive inhibitor design.

Saar KL. et al, (2023), Proc Natl Acad Sci U S A, 120

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