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Search results (195)

« Back to Publications

The Heterocycle Isostere Explorer: A Computational Tool for the Discovery of Novel Aromatic Heterocyclic Isosteres.

Holland MTO. et al, (2026), J Med Chem

Assessing Aβ-independent effects of Module 42 on immune function in vitro.

Ajith I. et al, (2026), Alzheimers Dement, 22

A BRET biosensor for measuring uncompetitive engagement of PRMT5 complexes in cells.

Rothweiler EM. et al, (2025), Nat Commun, 16

Antifungal, antibacterial, and anti-inflammatory activity of glycerol dithionomonolaurate, an analog of glycerol monolaurate.

Schlievert PM. et al, (2025), mSphere, 10

MR1-ligand cross-linking identifies vitamin B6 metabolites as TCR-reactive antigens.

Schmidlin T. et al, (2025), Cell Rep Methods, 5

Transfer Learning for Heterocycle Retrosynthesis.

Wieczorek E. et al, (2025), J Chem Inf Model, 65, 7851 - 7861

A patent review of peptidylarginine deiminase 4 (PAD4) inhibitors (2014-present).

Aiken SG. et al, (2025), Expert Opin Ther Pat, 35, 611 - 621

Inhibition of MLLT1 limits growth of MLL-AF4 leukaemias without killing healthy haematopoietic stem cells

Rajhansa S. et al, (2025)

Drug repurposing in amyotrophic lateral sclerosis (ALS).

Carroll E. et al, (2025), Expert Opin Drug Discov, 20, 447 - 464

Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor.

O'Brien DP. et al, (2025), J Proteome Res, 24, 479 - 490

The Chemical Probes Portal - 2024: update on this public resource to support best-practice selection and use of small molecules in biomedical research.

Sanfelice D. et al, (2025), Nucleic Acids Res, 53, D1663 - D1669

Luminescence-based complementation assay to assess target engagement and cell permeability of glycolate oxidase (HAO1) inhibitors.

Mackinnon SR. et al, (2025), Biochimie, 228, 71 - 81

Identification and characterization of human KALRN mRNA and Kalirin protein isoforms.

Mould AW. et al, (2024), Cereb Cortex, 34

MITOCHONDRIAL DYSFUNCTION IN NEUROSCIENCE: RECENT DEVELOPMENTS IN USP30 INHIBITORS

Worm K. et al, (2024), 59, 37 - 58

Covalent Inhibitors of S100A4 Block the Formation of a Pro-Metastasis Non-Muscle Myosin 2A Complex.

Giroud C. et al, (2024), J Med Chem, 67, 18943 - 18956

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