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Search results (201)

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Inhibition of MLLT1 limits growth of KMT2A::AFF1 leukaemias without killing healthy haematopoietic stem cells.

Rajhansa S. et al, (2026), Exp Hematol

Pleural fluid neutrophil extracellular traps are associated with disease severity and risk of one-year mortality in pleural infection. An observational, international, multicohort study (TORPIDS-3).

Chu JY. et al, (2026), Eur Respir J

KDM3A catalyses the oxidation of acetyl-lysine to hydroxyacetyl-lysine on histone H3K9.

Belle R. et al, (2026), Nat Chem

The Heterocycle Isostere Explorer: A Computational Tool for the Discovery of Novel Aromatic Heterocyclic Isosteres.

Holland MTO. et al, (2026), J Med Chem, 69, 4408 - 4423

Assessing Aβ-independent effects of Module 42 on immune function in vitro.

Ajith I. et al, (2026), Alzheimers Dement, 22

A BRET biosensor for measuring uncompetitive engagement of PRMT5 complexes in cells.

Rothweiler EM. et al, (2025), Nat Commun, 16

Antifungal, antibacterial, and anti-inflammatory activity of glycerol dithionomonolaurate, an analog of glycerol monolaurate.

Schlievert PM. et al, (2025), mSphere, 10

MR1-ligand cross-linking identifies vitamin B6 metabolites as TCR-reactive antigens.

Schmidlin T. et al, (2025), Cell Rep Methods, 5

Transfer Learning for Heterocycle Retrosynthesis.

Wieczorek E. et al, (2025), J Chem Inf Model, 65, 7851 - 7861

A patent review of peptidylarginine deiminase 4 (PAD4) inhibitors (2014-present).

Aiken SG. et al, (2025), Expert Opin Ther Pat, 35, 611 - 621

Inhibition of MLLT1 limits growth of MLL-AF4 leukaemias without killing healthy haematopoietic stem cells

Rajhansa S. et al, (2025)

Drug repurposing in amyotrophic lateral sclerosis (ALS).

Carroll E. et al, (2025), Expert Opin Drug Discov, 20, 447 - 464

Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor.

O'Brien DP. et al, (2025), J Proteome Res, 24, 479 - 490

The Chemical Probes Portal - 2024: update on this public resource to support best-practice selection and use of small molecules in biomedical research.

Sanfelice D. et al, (2025), Nucleic Acids Res, 53, D1663 - D1669

A Live Cell BRET Probe to Quantify PRMT5-MTA Uncompetitive Target Engagement

Rothweiler E. et al, (2025)

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