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- Work starts on international EUbOPEN chemogenomics effort
- The Centre for Medicines Discovery is launched
- TargetDB: summarising target information
- Crystal structure of SARS-CoV-2 nsp13 (helicase)
- COVID Moonshot – aiming to develop novel small molecule inhibitors targeting SARS-CoV-2
- CMD begins project to revolutionise drug discovery using AI
- Wyatt Yue awarded 2021 Harrington UK Rare Disease Scholar Awards
- Structural Biology identifies new information to accelerate structure-based drug design against Covid-19
- TBXT: A new Target Enabling package for rare disease
- Structure of the helicase core of Werner helicase, a key target in microsatellite instability cancers (new paper published)
- Oxford ramps up COVID-19 testing capability
- The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks (new paper published)
- The deubiquitylase USP9X controls ribosomal stalling (new paper published)
- ALK2 Receptor Kinase Association with FKBP12.6 Is Structurally Conserved with the ALK2-FKBP12 Complex
- Exscientia and the University of Oxford announce partnership to develop treatments for Alzheimer’s disease
- Challenges and Opportunities for Drug Repositioning in Fibrodysplasia Ossificans Progressiva
- Deubiquitinase (DUB) profiling goes high-throughput
- Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva
- Chemogenomics for drug discovery: clinical molecules from open access chemical probes
- Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family
- How can X-ray technology help in Covid research?
- Ubiquitin protease 28, a potential drug target in squamous lung carcinoma
- Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection
- 2021 CMD Student Symposium
- Ubiquitin ligases: guardians of mammalian development
- Fragment Hotspot Mapping to Identify Selectivity-Determining Regions between Related Proteins (new paper published)
- Sequence and structural variations determining the recruitment of WNK kinases to the KLHL3 E3 ligase (new paper published)
- Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation (new paper published)
- Congratulations to DPhil student Eva Dalietou
- Congratulations to our DPhil student Amber Truepenny
- The Rainwater grant has been signed
- FOP Friends lab visit
- Research reveals the first molecular understanding of BIRC6 – an essential regulator of cell death
- Research reveals basis for KEAP1-CUL3 E3 ligase assembly and inhibition by CDDO
- Discovery of a chemical probe for CDKL5 demonstrates role in hippocampal CA1 physiology
- The solute carrier SPNS2 recruits PI(4,5)P2 to synergistically regulate transport of sphingosine-1-phosphate
- Leonidas Koukouflis
- John Davis
- Paul Brennan
- Frank von Delft
- Oleg Fedorov
- Alex Bullock
- Jon Elkins
- Kilian Huber
- Benedikt Kessler
- John Davis
- Cassandra Adams
- Annette von Delft
- Thomas Christott
- Eleanor Williams
- Lucas Ferreira
- Donatella Di Rienzo
- Thomas Smith
- Grace Gregory
- Matteo Ferla
- Michael Fairhead
- Lizbe Koekemoer
- Elizabeth MacLean
- Kate Humphrey
- Gavin McKinley
- Rod Chalk
- Leslye Roca Burgos
- Dong Wang
- Ashley Pike
- Roslin Adamson
- Jesper Hansen
- Gamma Chi
- Huanyu Li
- Karly Aitmakhanova
- Emma Murphy
- Nathan Wright
- Sneha Anand
- William Bradshaw
- Vittorio Katis
- Joseph Newman
- Charline Giroud
- Philip Charles
- Andreas Damianou
- Roman Fischer
- Raphael Heilig
- Svenja Hester
- Hannah Jones
- Darragh O'Brien
- Hannah Scott
- Paolo Spingardi
- Adam Thorne
- Bohan Yu
- Zhanru Yu
- Karolina Rygiel
- Anna Cederbalk
- Katherine England
- Tryfon Zarganis-Tzitzikas
- William Foster
- Rachael Brown
- Vicki Gamble
- Mihaela Smilova
- Chas Bountra
- Conor Wild
- Tamas Szommer
- Tom Grimes
- Franziska Guenther
- Hector Veremis
- Sohaib Nizami
- James Taylor
- Zhuoyao Chen
- David Cruz Walma
- Melissa Sweeney
- Ashley Ramdass
- Evmorfia Dalietou
- David Sauer
- Brian Marsden
- Milan Fowkes
- Xiangrong Chen
- Gemma Jennings
- Eszter Dombi
- Ahmad Alalti
- Daniel Ebner
- Magda Wolna
- Val Millar
- Elena Navarro Guerrero
- Stephanie Hatch
- William Seaton-Burn
- Lap Tse
- Julien Cros
- Emma Mead
- Alice Di Pasquale
- Lynn Wambua
- Dorota Nawrot
- Annapoorna Kannan
- Eboni Bucknor
- James Henderson
- Margarida Ruas
- Claire Martin
- Nirmal Sampathkumar
- Maciej Kliszczak
- Katerina Gospodinova
- Alexander Wilkes
- Laura Ortega Varga
- Adam Smith
- Gonzalo Vera Namuncura
- Anuja Bothra
- Emma Kennedy
- Michael Lowe
- Annie Webster
- Shania Ibarra
- Bindhu Lakshminarayana
- Ishita Ajith
- Matthew Holland
- Mia Callens
- Amber Truepenny
- Jesus Baltanas Copado
- Anjhu Nair
- Álvaro Vinals Guitart
- Qilong Wu
- Humaira Islam
- Jessica Dixon
- Korvus Wang
- Laurent Brooke
- Lee Harris
- Souvika Bakshi
- Kerry McLaughlin
- Roberta Baronio
- Hannah Dobbs