Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Publications

Accessory ESCRT-III proteins are conserved and selective regulators of Rab11a-exosome formation.

Marie PP. et al, (2023), J Extracell Vesicles, 12

Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B.

Skaist Mehlman T. et al, (2023), eLife, 12

Development of Selective ADAMTS-5 Peptide Substrates to Monitor Proteinase Activity

Fowkes MM. et al, (2023), Journal of Medicinal Chemistry

Discovery and Development Strategies for SARS-CoV-2 NSP3 Macrodomain Inhibitors

Schuller M. et al, (2023), Pathogens, 12, 324 - 324

Structural and biochemical characterization establishes a detailed understanding of KEAP1-CUL3 complex assembly

Adamson RJ. et al, (2023)

Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6

Dietz L. et al, (2023), Science

Small-molecule Polθ inhibitors provide safe and effective tumor radiosensitization in preclinical models

Rodriguez-Berriguete G. et al, (2023), Clinical Cancer Research

Discovery of a chemical probe to study implications of BPTF bromodomain inhibition in cellular and in vivo experiments.

Martinelli P. et al, (2023), ChemMedChem

Simultaneous identification of viruses and viral variants with programmable DNA nanobait.

Bošković F. et al, (2023), Nat Nanotechnol

Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2.

Gahbauer S. et al, (2023), Proc Natl Acad Sci U S A, 120

Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region.

Emmenegger M. et al, (2023), iScience

Activity-Based Protein Profiling (ABPP) for Cellular Deubiquitinase (DUB) and Inhibitor Profiling at Deep and High-Throughput Levels.

Jones HBL. et al, (2023), Methods Mol Biol, 2591, 101 - 122

CoPriNet: graph neural networks provide accurate and rapid compound price prediction for molecule prioritisation

Sanchez-Garcia R. et al, (2023), Digital Discovery

Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4.

Londregan AT. et al, (2022), J Med Chem

Crystal structures and fragment screening of SARS-CoV-2 NSP14 reveal details of exoribonuclease activation and mRNA capping and provide starting points for antiviral drug development.

Imprachim N. et al, (2022), Nucleic Acids Res

A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk.

Rottner AK. et al, (2022), Nat Genet

The use of a graph database is a complementary approach to a classical similarity search for identifying commercially available fragment merges

Wills S. et al, (2022)

Nilabh Shastri – Towards understanding classical and non-classical MHC-I antigen processing and presentation

Kessler BM., (2022), Cellular Immunology, 382, 104638 - 104638

Biallelic PRMT7 pathogenic variants are associated with a recognizable syndromic neurodevelopmental disorder with short stature, obesity, and craniofacial and digital abnormalities.

Cali E. et al, (2022), Genet Med

Single-cell transcriptomics defines an improved, validated monoculture protocol for differentiation of human iPSC to microglia.

Washer SJ. et al, (2022), Sci Rep, 12

Load More

1
2
3
4
5
6
7
...
»