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A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family.

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Baddock HT. et al, (2021), Nucleic Acids Res, 49, 9294 - 9309

Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition.

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Yosaatmadja Y. et al, (2021), Nucleic Acids Res, 49, 9310 - 9326

SPRTN protease-cleaved MRE11 decreases DNA repair and radiosensitises cancer cells.

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Na J. et al, (2021), Cell Death Dis, 12

The SNM1A DNA repair nuclease.

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Baddock HT. et al, (2020), DNA Repair (Amst), 95

RecQ helicases in DNA repair and cancer targets.

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Newman JA. and Gileadi O., (2020), Essays Biochem, 64, 819 - 830

STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers.

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van der Lelij P. et al, (2020), Life Sci Alliance, 3

Crystal Structure of the Werner’s Syndrome Helicase


Newman JA. et al, (2020)

Molecular basis of the activity of SinR Protein, the master regulator of biofilm formation in bacillus subtilis

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Newman JA. et al, (2013), Journal of Biological Chemistry, 288, 10766 - 10778

Dissection of the network of interactions that links RNA processing with glycolysis in the bacillus subtilis degradosome

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Newman JA. et al, (2012), Journal of Molecular Biology, 416, 121 - 136

RNase Y in Bacillus subtilis: A natively disordered protein that is the functional equivalent of RNase E from Escherichia coli

Journal article

Lehnik-Habrink M. et al, (2011), Journal of Bacteriology, 193, 5431 - 5441

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