Discovery of Conformationally Constrained ALK2 Inhibitors.
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Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1.
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Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays.
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A novel method to quantify fibrin-fibrin and fibrin-α2AP cross-links in thrombi formed from human trauma patient plasma.
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De novo variants in DENND5B cause a neurodevelopmental disorder.
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Optimized protocol for CRISPR knockout of human iPSC-derived macrophages.
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Tau depletion in human neurons mitigates Aβ-driven toxicity.
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Ng B. et al, (2024), Mol Psychiatry
A selection of Golden Gate vectors to simplify recombinant protein production inEscherichia coli
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A systems-based approach to uterine fibroids identifies differential splicing associated with abnormal uterine bleeding
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Protein Profiling of Placental Extracellular Vesicles in Gestational Diabetes Mellitus
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Risk of SARS-CoV-2 reinfection during multiple Omicron variant waves in the UK general population.
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Kidney Tissue Proteome Profiles in Short Versus Long Duration of Delayed Graft Function - A Pilot Study in Donation After Circulatory Death Donors
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Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2
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BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution.
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Discovery of PFI-6, a small-molecule chemical probe for the YEATS domain of MLLT1 and MLLT3.
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CD4 T cell contact drives macrophage cell cycle progression and susceptibility to lentiviral transduction
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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.
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A hybrid electrospun-extruded polydioxanone suture for tendon tissue regeneration.
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