Type I interferon regulation by USP18 is a key vulnerability in cancer
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Jové V. et al, (2024), iScience, 27
Unexpected Noncovalent Off-Target Activity of Clinical BTK Inhibitors Leads to Discovery of a Dual NUDT5/14 Antagonist.
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Balıkçı E. et al, (2024), J Med Chem
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity.
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Hamid MHBA. et al, (2024), Nat Immunol
Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor.
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Xiong Y. et al, (2024), J Med Chem
The binding and mechanism of a positive allosteric modulator of Kv3 channels.
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Liang Q. et al, (2024), Nat Commun, 15
Discovery of Conformationally Constrained ALK2 Inhibitors.
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González-Álvarez H. et al, (2024), J Med Chem
Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1.
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Imhoff RD. et al, (2024), J Med Chem
Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays.
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van Veggel L. et al, (2024), ACS Chem Neurosci
Dietary n-3 polyunsaturated fatty acids alter the number, fatty acid profile and coagulatory activity of circulating and platelet-derived extracellular vesicles: a randomized, controlled crossover trial.
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Bozbas E. et al, (2024), Am J Clin Nutr
A novel method to quantify fibrin-fibrin and fibrin-α2AP cross-links in thrombi formed from human trauma patient plasma.
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Morrow GB. et al, (2024), J Thromb Haemost
AZD1222 effectiveness against severe COVID-19 in individuals with comorbidity or frailty: The RAVEN cohort study.
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Meeraus W. et al, (2024), J Infect, 88
Optimized protocol for CRISPR knockout of human iPSC-derived macrophages.
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Navarro-Guerrero E. et al, (2024), STAR Protoc, 5
Tau depletion in human neurons mitigates Aβ-driven toxicity.
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Ng B. et al, (2024), Mol Psychiatry
A selection of Golden Gate vectors to simplify recombinant protein production inEscherichia coli
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Fairhead M. et al, (2024)
A systems-based approach to uterine fibroids identifies differential splicing associated with abnormal uterine bleeding
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Wang CY. et al, (2024)
Protein Profiling of Placental Extracellular Vesicles in Gestational Diabetes Mellitus
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Kandzija N. et al, (2024), International Journal of Molecular Sciences, 25, 1947 - 1947
Risk of SARS-CoV-2 reinfection during multiple Omicron variant waves in the UK general population.
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Wei J. et al, (2024), Nat Commun, 15
Kidney Tissue Proteome Profiles in Short Versus Long Duration of Delayed Graft Function - A Pilot Study in Donation After Circulatory Death Donors
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Lo Faro ML. et al, (2024), Kidney International Reports
Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2.
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Bradshaw WJ. et al, (2024), Structure