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Biotechnology

The Biotechnology group is interested in development of methods for high-throughput (HTP) screening and large scale production of proteins for structural and functional characterisation. We have established HTP cloning and expression systems for E. coli, insect (Baculovirus) and mammalian (BacMam and transient) cells, multiple purification strategies using ÄKTA systems and quality control validation by mass spectrometry. We have significant experience in producing human proteins, intracellular, secreted and integral membrane proteins (IMPs), multiprotein complexes as well as LPS-free antigens and biomarkers.

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